BioMarin updates the Multicenter and Multinational Clinical Study 111-901
The "Multicenter, Multinational Clinical Assessment Study for Pediatric Patients With Achondroplasia" is a prospective observational study. This study's code name is 111-901.
The aim of this study is to collect systematic growth measurements of the children in order to collect data to better understand the natural history of achondroplasia.
Children between 2 and 13 years old can be enrolled in the 111-901 study. The measurements take place every 3 months and can go for up to 60 months (or 5 years).
BMN-111 will not be administered in this study. Yet, only children that participate in the study 111-901 can be enrolled in the drug study afterwards, with the code 111-301, in which BMN-111 will be administrated to 50% of participants while the others will receive a placebo.

Credits: Brakefield R. Observational Studies and Experiments, 2015 |
Locations:
United States, |
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Harbor-UCLA Medical Center | |
Los Angeles, California, United States, 90048 | |
Contact: Nathalia Patritti Cressey, Study Coord 310-781-3682 ext Office | |
Contact 310-597-1960 ext Cell | |
Principal Investigator: Patti Dickson, MD | |
Children's Hospital and Research Center Oakland | |
Oakland, California, United States, 94609 | |
Contact: Jacqueline Madden, Study Coord 510-428-3885 ext 5745 | |
This email address is being protected from spambots. You need JavaScript enabled to view it. | |
Children's Hospital Colorado | |
Aurora, Colorado, United States, 80045 | |
Contact: Laurel Ware, BSN 720-777-5378 This email address is being protected from spambots. You need JavaScript enabled to view it. |
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Principal Investigator: Gary Bellus | |
Nemours/Alfred I. duPont Hospital for Children | |
Wilmington, Delaware, United States, 19803 | |
Contact: Cassie Brown, Study Coord 302-298-7930 This email address is being protected from spambots. You need JavaScript enabled to view it. |
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Contact: Michael Bober, MD | |
Emory University | |
Decatur, Georgia, United States, 30033 | |
Contact: Elizabeth Smith, Study Coord This email address is being protected from spambots. You need JavaScript enabled to view it. |
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Contact: William Wilcox, MD This email address is being protected from spambots. You need JavaScript enabled to view it. |
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Ann and Robert H Lurie Children's Hospital of Chicago | |
Chicago, Illinois, United States, 60614 | |
Contact: Victoria Sanders, Study Coord 312-227-6120 | |
Indiana University, Riley Children's Hospital | |
Indianapolis, Indiana, United States, 46202 | |
Contact: Susan Romie 317-278-6650 This email address is being protected from spambots. You need JavaScript enabled to view it. |
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Principal Investigator: David Weaver, MD | |
Johns Hopkins McKusick- Institute of Genetic Medicine | |
Baltimore, Maryland, United States, 21287 | |
Contact: Adekemi Alade, Study Coord This email address is being protected from spambots. You need JavaScript enabled to view it. |
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Contact: Kira Lurman, Study Coord This email address is being protected from spambots. You need JavaScript enabled to view it. |
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University of Missouri | |
Columbia, Missouri, United States, 65201 | |
Contact: Vicki L Jones, Study Coord 573-882-7583 This email address is being protected from spambots. You need JavaScript enabled to view it. |
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Contact: Daniel G Hoernschemeyer, MD 573-882-1351 | |
Principal Investigator: Daniel G Hoernschemeyer, MD | |
Cincinnati Children's Hospital Medical Center | |
Cincinnati, Ohio, United States, 45229 | |
Contact: Racheal Powers 800-647-4805 | |
Principal Investigator: Howard Saal, MD | |
Vanderbilt University | |
Nashville, Tennessee, United States, 37232 | |
Contact: LeeAnna Melton, Study Coord 615-343-6761 This email address is being protected from spambots. You need JavaScript enabled to view it. |
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Baylor College of Medicine | |
Houston, Texas, United States, 77030 | |
Contact: Catherine Loffredo, Study Coord This email address is being protected from spambots. You need JavaScript enabled to view it. |
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Seattle Children's Hospital | |
Seattle, Washington, United States, 98105 | |
Contact: Tressa Mattioli-Lewis This email address is being protected from spambots. You need JavaScript enabled to view it. |
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Contact: Klane White, MD This email address is being protected from spambots. You need JavaScript enabled to view it. |
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Principal Investigator: Klane White, MD | |
Medical College of Wisconsin, Children's Hospital | |
Milwaukee, Wisconsin, United States, 53226 | |
Contact: Paula Engelking 414-266-3289 This email address is being protected from spambots. You need JavaScript enabled to view it. |
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Contact: Donald Basel, MD This email address is being protected from spambots. You need JavaScript enabled to view it. |
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Principal Investigator: Donald Basel, MD |
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Australia, Victoria | |
Murdoch Children's Research Institute | |
Parkville, Victoria, Australia, 3052 |
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France | |
Institut Necker | |
Paris, France, 75015 | |
Contact: Kim-Hahn Le Quan Sang, MD 33 1 44 49 59 51 This email address is being protected from spambots. You need JavaScript enabled to view it. |
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Principal Investigator: Valerie Cormier-Daire, MD |
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Spain | |
Institut Catala de Traumatologica I Medicina de l'Esport | |
Barcelona, Spain, 08028 | |
Contact: Miriam Perez +34 932 05 43 62 ext 21148 This email address is being protected from spambots. You need JavaScript enabled to view it. |
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Contact: Ignacio Ginebreda +34 619 21 35 77 This email address is being protected from spambots. You need JavaScript enabled to view it. |
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Principal Investigator: Ignacio Ginebreda | |
Hospital Sant Joan de Deu Barcelona | |
Barcelona, Spain, 08950 | |
Contact: Jose Maria de Bergua +34 650 80 60 71 | |
Contact: Rosendo Ullot +34 650 80 60 71 This email address is being protected from spambots. You need JavaScript enabled to view it. |
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Principal Investigator: Rosendo Ullot | |
Hospital Universitario Virgen de la Victoria | |
Málaga, Spain, 29010 | |
Contact: Antonio Leiva +34 646 56 87 89 | |
Contact: Felipe Luna +34 607 85 81 22 | |
Principal Investigator: Felipe Luna |
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Turkey | |
Acibadem University School of Medicine | |
Istanbul, Turkey, 34752 | |
Contact: Beyzanur Gonenc +90 532 300 09 13 This email address is being protected from spambots. You need JavaScript enabled to view it. |
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Contact: Burcu Menderes +90 555 313 40 86 This email address is being protected from spambots. You need JavaScript enabled to view it. |
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Principal Investigator: Yesemin Alanay, MD | |
Sub-Investigator: Selda Karaayvaz |
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United Kingdom | |
Guy's and St. Thomas NHS Foundation Trust Evelina Children's Hospital | |
London, United Kingdom, SE1 9RT | |
Principal Investigator: Melita Irving, MD |
Information available on Clinicaltrials.gov